High levels of microplastics found in human brains
By Douglas Main
A new study has found high concentrations of tiny plastic particles in human brain samples, with levels appearing to climb over time.
By Douglas Main
A new study has found high concentrations of tiny plastic particles in human brain samples, with levels appearing to climb over time.
By Carey Gillam
People diagnosed with infertility and certain cancers may have to blame the very air they breathe, according to a new report that adds to evidence that tiny plastic particles in air pollution and other environmental sources could be causing these and other diseases and illnesses.
By Carey Gillam
Exposure to a widely used weed killing chemical could be having “persistent, damaging effects” on brain health, according to a new study.
By Carey Gillam, Margot Gibbs and Elena DeBre
In 2017, two United Nations experts called for a treaty to strictly regulate dangerous pesticides, which they said were a “global human rights concern”, citing scientific research showing pesticides can cause cancers, Parkinson’s disease, Alzheimer’s, and other health problems.
By Douglas Main
A growing body of scientific evidence shows that microplastics are accumulating in critical human organs, including the brain, alarming findings that highlight a need for more urgent actions to rein in plastic pollution, researchers say.
Different studies have detected tiny shards and specks of plastics in human lungs, placentas, reproductive organs, livers, kidneys, knee and elbow joints, blood vessels, and bone marrow.
Given the research findings, “it is now imperative to declare a global emergency” to deal with plastic pollution, said Sedat Gündoğdu, who studies microplastics at Cukurova University in Turkey.
Humans are exposed to microplastics – defined as fragments smaller than five millimeters in length – and the chemicals used to make plastics from widespread plastic pollution in air, water, and even food.
The health hazards of microplastics within the human body are not yet well-known. Recent studies are just beginning to suggest these particles could increase the risk of various conditions such as oxidative stress, which can lead to cell damage and inflammation, as well as cardiovascular disease.
Animal studies have also linked microplastics to fertility issues, various cancers, a disrupted endocrine and immune system, and impaired learning and memory.
There are currently no governmental standards for plastic particles in food or water in the United States. The Environmental Protection Agency is working on crafting guidelines for measuring them, and has been giving out grants since 2018 to develop new ways to quickly detect and quantify them.
Finding microplastics in more and more human organs “raises a lot of concerns,” given what we know about health effects in animals, studies of human cells in the lab, and emerging epidemiological studies, said Bethanie Carney Almroth, an ecotoxicologist at the University of Gothenburg in Sweden. “It’s scary, I’d say.”
By Carey Gillam
California has moved a step closer to banning the controversial weed killing chemical paraquat after a key state legislative committee on Thursday allowed the measure to proceed.
The ban would take effect Jan. 1, 2026, outlawing the “use, manufacture, sale, delivery, holding, or offering for sale in commerce” of any pesticide product that contains paraquat. The bill provides for a process that allows state regulators to reevaluate paraquat and potentially reapprove it with or without new restrictions.
A chief concern cited by backers of the bill is research linking chronic paraquat exposure to Parkinson’s disease, an incurable and debilitating brain disease considered a top cause of death in the United States.
Several thousand farmers, agricultural workers and others are suing paraquat maker Syngenta, alleging they developed Parkinson’s because of long-term chronic effects of paraquat.
“California is the breadbasket of the nation. Farm workers put food on our table, and we should do everything we can to make their jobs safer,” California Assemblymember Laura Friedman said. “No one should run the risk of chemical exposure on the job leading to their contracting Parkinson’s disease.”
Friedman, who partnered with the Environmental Working Group (EWG) to introduce the measure, said it passed “not only because banning paraquat is the right thing to do,” but also because there are “readily available, safer, affordable alternatives.”
The movement of the bill out of the appropriations committee this week now sets it up for a vote by the full Assembly next week. A vote has to be completed by Friday, May 24, in order for the measure to be moved to the state Senate for consideration. A majority of 80 Assembly members is needed to keep the bill alive.
By Carey Gillam
Global chemical giant Syngenta has sought to secretly influence scientific research regarding links between its top-selling weed killer and Parkinson’s, internal corporate documents show.
While numerous independent researchers have determined that the weed killer, paraquat, can cause neurological changes that are hallmarks of Parkinson’s, Syngenta has always maintained that the evidence linking paraquat to Parkinson’s disease is “fragmentary” and “inconclusive.”
But the scientific record they point to as proof of paraquat’s safety is one that Syngenta officials, scientists and lawyers in the US and the UK have worked over decades to create, and at times, covertly manipulate, according to the trove of internal Syngenta files reviewed by the The New Lede in a collaboration with The Guardian.
The files reveal an array of tactics, including enlisting a prominent UK scientist and other outside researchers who authored scientific literature that did not disclose any involvement with Syngenta; misleading regulators about the existence of unfavorable research conducted by its own scientists; and engaging lawyers to review and suggest edits for scientific reports in ways that downplayed worrisome findings.
The files also show that Syngenta created what officials called a “PQ SWAT team” to be ready to respond to new independent scientific reports that could interfere with Syngenta’s “freedom to sell” paraquat. The group, also referred to as Paraquat Communications Management Team,” was to convene “immediately on notification” of the publication of a new study, “triage the situation,” and plan a response, including commissioning a “scientific critique.”
A key goal was to “create an international scientific consensus against the hypothesis that paraquat is a risk factor for Parkinson’s disease,” the documents state.
In another example of a company tactic, an outside lawyer hired by Syngenta to work with its scientists was asked to review and suggest edits on internal meeting minutes regarding paraquat safety. The lawyer pushed scientists to alter “problematic language” and scientific conclusions deemed “unhelpful” to the corporate defense of paraquat.
By Carey Gillam
When US regulators issued a 2019 assessment of the widely used farm chemical paraquat, they determined that even though multiple scientific studies linked the chemical to Parkinson’s disease, that work was outweighed by other studies that did not find such links. Overall, the weight of scientific evidence was “insufficient” to prove paraquat causes the brain disease, officials with the US Environmental Protection Agency (EPA) declared.
The EPA reiterated its assessment in a 2021 report. The agency said after extensive analysis of numerous factors, including concerns about Parkinson’s risk, it determined farmers could safely continue to apply the weed killer across millions of US acres to help in the production of soybeans, corn, cotton and an array of other crops.
The determination has been significant for Syngenta, the longtime maker of paraquat weed killers. The company is facing calls in the US for a paraquat ban, as well as more than 2,000 legal claims brought by farmers and others alleging they developed Parkinson’s disease because of their exposure to paraquat.
Syngenta cites the EPA assessment of the science on paraquat in defense of the pesticide, and says scientific research “does not support” a causal relationship between the chemical and the disease. On a Syngenta-run paraquat information website, the company highlights several studies it says also backs that position, including many conducted by company scientists or by outside scientists who received company funding for their work.
Last week the Guardian and The New Lede reported that internal corporate records show Syngenta had knowledge of science linking paraquat to Parkinson’s decades ago but sought both to refute the evidence with various secret tactics. The documents are available at the Paraquat Papers Media Library.
US farmworker, health and environmental advocacy groups say in contrast to the corporate science, research conducted by independent scientists provides abundant evidence of paraquat’s ability to cause Parkinson’s and other health dangers, and the EPA is improperly discounting that body of research.
More than 50 groups have called for the US to follow the lead of dozens of other countries in banning paraquat. The Michael J. Fox Foundation for Parkinson’s Research submitted a petition to the EPA with 107,000 signatories calling for a ban. The foundation cited a study that found people exposed to paraquat in their teens or as young adults had an increased Parkinson’s risk of 200 to 600 percent, depending on the overall exposure.
By Carey Gillam and Aliya Uteuova
For more than 50 years, Swiss chemical giant Syngenta has manufactured and marketed a widely used weed killing chemical called paraquat, and for much of that time the company has been dealing with external concerns that long-term exposure to the chemical may cause the dreaded, incurable brain ailment known as Parkinson’s disease.
Syngenta has repeatedly told customers and regulators that scientific research does not prove a connection between its weed killer and the disease, insisting that the chemical does not readily cross the blood-brain barrier, and does not affect brain cells in ways that cause Parkinson’s.
But a cache of internal corporate documents dating back to the 1950s obtained by The New Lede in a reporting collaboration with the Guardian suggests that the public narrative put forward by Syngenta and the corporate entities that preceded it has at times contradicted the company’s own research and knowledge.
And though the documents reviewed do not show that Syngenta’s scientists and executives accepted and believed that paraquat can cause Parkinson’s, they do show a corporate focus on strategies to protect product sales, refute external scientific research and influence regulators.
In one defensive tactic, the documents lay out how the company worked behind the scenes to try to keep a highly regarded scientist from sitting on an advisory panel for the US Environmental Protection Agency (EPA). The agency is the chief US regulator for paraquat and other pesticides. Company officials wanted to make sure the efforts could not be traced back to Syngenta, the documents show.
And the documents show that insiders feared they could face legal liability for long-term, chronic effects of paraquat as long ago as 1975. One company scientist called the situation “a quite terrible problem,” for which “some plan could be made….”